diff --git a/include/uv/unix.h b/include/uv/unix.h
index 9080352d..3a131638 100644
--- a/include/uv/unix.h
+++ b/include/uv/unix.h
@@ -405,11 +405,25 @@ typedef struct {
 #else
 # define UV_FS_O_CREAT        0
 #endif
-#if defined(O_DIRECT)
+
+#if defined(__linux__) && defined(__arm__)
+# define UV_FS_O_DIRECT       0x10000
+#elif defined(__linux__) && defined(__m68k__)
+# define UV_FS_O_DIRECT       0x10000
+#elif defined(__linux__) && defined(__mips__)
+# define UV_FS_O_DIRECT       0x08000
+#elif defined(__linux__) && defined(__powerpc__)
+# define UV_FS_O_DIRECT       0x20000
+#elif defined(__linux__) && defined(__s390x__)
+# define UV_FS_O_DIRECT       0x04000
+#elif defined(__linux__) && defined(__x86_64__)
+# define UV_FS_O_DIRECT       0x04000
+#elif defined(O_DIRECT)
 # define UV_FS_O_DIRECT       O_DIRECT
 #else
 # define UV_FS_O_DIRECT       0
 #endif
+
 #if defined(O_DIRECTORY)
 # define UV_FS_O_DIRECTORY    O_DIRECTORY
 #else