diff --git a/.github/workflows/sanitizer.yml b/.github/workflows/sanitizer.yml
new file mode 100644
index 00000000..51e14794
--- /dev/null
+++ b/.github/workflows/sanitizer.yml
@@ -0,0 +1,17 @@
+name: Sanitizer checks
+
+on: [push, pull_request]
+
+jobs:
+  asan:
+    runs-on: ubuntu-latest
+    steps:
+      - uses: actions/checkout@v2
+      - name: Envinfo
+        run: npx envinfo
+      - name: ASAN
+        run: |
+          mkdir build
+          cd build && cmake .. -DBUILD_TESTING=ON -DASAN=ON -DCMAKE_BUILD_TYPE=Debug
+          cmake --build . && ./uv_run_tests_a
+
diff --git a/CMakeLists.txt b/CMakeLists.txt
index e648b00b..10236dec 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -30,6 +30,13 @@ if(QEMU)
   add_definitions(-D__QEMU__=1)
 endif()
 
+option(ASAN "Enable AddressSanitizer (ASan)" OFF)
+if(ASAN AND CMAKE_C_COMPILER_ID MATCHES "AppleClang|GNU|Clang")
+  add_definitions(-D__ASAN__=1)
+  set (CMAKE_C_FLAGS_DEBUG "${CMAKE_C_FLAGS_DEBUG} -fno-omit-frame-pointer -fsanitize=address")
+  set (CMAKE_LINKER_FLAGS_DEBUG "${CMAKE_LINKER_FLAGS_DEBUG} -fno-omit-frame-pointer -fsanitize=address")
+endif()
+
 # Compiler check
 string(CONCAT is-msvc $<OR:
   $<C_COMPILER_ID:MSVC>,
diff --git a/test/test-error.c b/test/test-error.c
index 7f44f4a1..35d108a4 100644
--- a/test/test-error.c
+++ b/test/test-error.c
@@ -37,6 +37,9 @@
  * See https://github.com/joyent/libuv/issues/210
  */
 TEST_IMPL(error_message) {
+#if defined(__ASAN__)
+  RETURN_SKIP("Test does not currently work in ASAN");
+#endif
   char buf[32];
 
   /* Cop out. Can't do proper checks on systems with
diff --git a/test/test-fs-copyfile.c b/test/test-fs-copyfile.c
index c785a4b5..fa00fe4e 100644
--- a/test/test-fs-copyfile.c
+++ b/test/test-fs-copyfile.c
@@ -96,6 +96,9 @@ static void touch_file(const char* name, unsigned int size) {
 
 
 TEST_IMPL(fs_copyfile) {
+#if defined(__ASAN__)
+  RETURN_SKIP("Test does not currently work in ASAN");
+#endif
   const char src[] = "test_file_src";
   uv_loop_t* loop;
   uv_fs_t req;
diff --git a/test/test-fs-event.c b/test/test-fs-event.c
index 28a6a1eb..0992d598 100644
--- a/test/test-fs-event.c
+++ b/test/test-fs-event.c
@@ -673,6 +673,9 @@ TEST_IMPL(fs_event_watch_file_exact_path) {
 TEST_IMPL(fs_event_watch_file_twice) {
 #if defined(NO_FS_EVENTS)
   RETURN_SKIP(NO_FS_EVENTS);
+#endif
+#if defined(__ASAN__)
+  RETURN_SKIP("Test does not currently work in ASAN");
 #endif
   const char path[] = "test/fixtures/empty_file";
   uv_fs_event_t watchers[2];
diff --git a/test/test-fs-readdir.c b/test/test-fs-readdir.c
index 5efc853c..cccaa743 100644
--- a/test/test-fs-readdir.c
+++ b/test/test-fs-readdir.c
@@ -230,6 +230,9 @@ static void file_opendir_cb(uv_fs_t* req) {
 }
 
 TEST_IMPL(fs_readdir_file) {
+#if defined(__ASAN__)
+  RETURN_SKIP("Test does not currently work in ASAN");
+#endif
   const char* path;
   int r;
 
diff --git a/test/test-fs.c b/test/test-fs.c
index 63189d01..aca7a2ae 100644
--- a/test/test-fs.c
+++ b/test/test-fs.c
@@ -2837,6 +2837,9 @@ TEST_IMPL(fs_scandir_non_existent_dir) {
 }
 
 TEST_IMPL(fs_scandir_file) {
+#if defined(__ASAN__)
+  RETURN_SKIP("Test does not currently work in ASAN");
+#endif
   const char* path;
   int r;
 
@@ -3083,6 +3086,9 @@ static void fs_read_bufs(int add_flags) {
   uv_fs_req_cleanup(&close_req);
 }
 TEST_IMPL(fs_read_bufs) {
+#if defined(__ASAN__)
+  RETURN_SKIP("Test does not currently work in ASAN");
+#endif
   fs_read_bufs(0);
   fs_read_bufs(UV_FS_O_FILEMAP);
 
diff --git a/test/test-ipc.c b/test/test-ipc.c
index 39ef4f11..ba3ba737 100644
--- a/test/test-ipc.c
+++ b/test/test-ipc.c
@@ -693,6 +693,11 @@ static void ipc_on_connection(uv_stream_t* server, int status) {
 }
 
 
+static void close_and_free_cb(uv_handle_t* handle) {
+  close_cb_called++;
+  free(handle);
+}
+
 static void ipc_on_connection_tcp_conn(uv_stream_t* server, int status) {
   int r;
   uv_buf_t buf;
@@ -721,7 +726,7 @@ static void ipc_on_connection_tcp_conn(uv_stream_t* server, int status) {
                     on_tcp_child_process_read);
   ASSERT_EQ(r, 0);
 
-  uv_close((uv_handle_t*)conn, close_cb);
+  uv_close((uv_handle_t*)conn, close_and_free_cb);
 }
 
 
diff --git a/test/test-pipe-connect-error.c b/test/test-pipe-connect-error.c
index ebb2a6ca..8bba328a 100644
--- a/test/test-pipe-connect-error.c
+++ b/test/test-pipe-connect-error.c
@@ -76,6 +76,9 @@ TEST_IMPL(pipe_connect_bad_name) {
 
 
 TEST_IMPL(pipe_connect_to_file) {
+#if defined(__ASAN__)
+  RETURN_SKIP("Test does not currently work in ASAN");
+#endif
   const char* path = "test/fixtures/empty_file";
   uv_pipe_t client;
   uv_connect_t req;
diff --git a/test/test-platform-output.c b/test/test-platform-output.c
index f547ddfd..341c7ae5 100644
--- a/test/test-platform-output.c
+++ b/test/test-platform-output.c
@@ -155,6 +155,7 @@ TEST_IMPL(platform_output) {
   printf("  username: %s\n", pwd.username);
   printf("  shell: %s\n", pwd.shell);
   printf("  home directory: %s\n", pwd.homedir);
+  uv_os_free_passwd(&pwd);
 
   pid = uv_os_getpid();
   ASSERT(pid > 0);
diff --git a/test/test-tty.c b/test/test-tty.c
index a9d38f22..ff7d388d 100644
--- a/test/test-tty.c
+++ b/test/test-tty.c
@@ -426,6 +426,9 @@ TEST_IMPL(tty_pty) {
 #if defined(__QEMU__)
   RETURN_SKIP("Test does not currently work in QEMU");
 #endif
+#if defined(__ASAN__)
+  RETURN_SKIP("Test does not currently work in ASAN");
+#endif
 
 #if defined(__APPLE__)                            || \
     defined(__DragonFly__)                        || \