diff --git a/config-unix.mk b/config-unix.mk
index 8fe7254c..759be4e0 100644
--- a/config-unix.mk
+++ b/config-unix.mk
@@ -50,6 +50,7 @@ endif
 ifeq (Darwin,$(uname_S))
 EV_CONFIG=config_darwin.h
 EIO_CONFIG=config_darwin.h
+CPPFLAGS += -D__DARWIN_64_BIT_INO_T=1
 CPPFLAGS += -Isrc/ares/config_darwin
 LINKFLAGS+=-framework CoreServices
 OBJS += src/unix/darwin.o
diff --git a/uv.gyp b/uv.gyp
index 83129b5c..88cee32b 100644
--- a/uv.gyp
+++ b/uv.gyp
@@ -9,6 +9,9 @@
           'EIO_STACKSIZE=262144'
         ],
         'conditions': [
+          ['OS=="mac"', {
+            'defines': ['__DARWIN_64_BIT_INO_T=1'],
+          }],
           ['OS=="solaris"', {
             'cflags': ['-pthreads'],
             'ldlags': ['-pthreads'],